Hospital-acquired infections are commonly caused by the contamination of public areas with fluid droplets from patients during coughing and sneezing. Other public plates such as shopping malls and schools are also faced with the same issue. The Self-sanitizing door handle generates reactive species photo-catalytically to inactivate bacteria on the surface, which means the TiO2 coating is never used up. The bactericidal effect could remain as long as the coating is activated by UV-light.